Learn more about Bridelia uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Bridelia. Asas, Assas, Bridelia cathartica, Bridelia ferruginea , Bridelia grandis, Bridelia micrantha, Bridelia. In present study we explore dose dependent effects of Bridelia ferruginea on hematological parameters. The hematological responses of albino. A review of Bridelia ferruginea, Combretum glutinosum and Mitragina inermis plants used in zootherapeutic remedies in West Africa: historical.

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Bull World Health Organ.

Evidence-Based Complementary and Alternative Medicine

However, consumption of herbal products or traditional medicines by various ethnic groups involves challenges and drawbacks, including several adverse effects, sometimes life-threatening, thus putting into question the safety of herbal remedies Soejarto, ; Elvin-Lewis, The absorbance bridleia read at nm. Materials and Methods 2. At the end of the incubation period, supernatants were collected for nitrite measurement with the Griess assay.

Potential consequences of plant nridelia in the United States on the current and future availability of prescription drugs. The plates were incubated at 27 o C for 72 hrs. Discussion Acute toxicity LD 50 testing has been widely used, though often criticized as a parameter for assessing toxicity Lorke, ; Klaassen, ; Timbrel, Necessary precautions were taken to avoid contaminations during the experiment.

briedlia Clinical Haematology in Medical Practice. There were no significant differences in the animals and organ weights, hematological and biochemical parameters in the treated groups compared to the control group.


Bridelia ferruginea – Useful Tropical Plants

Measurement of the activity of serum antioxidant enzymes and malondialdehyde MDA Determination of superoxide dismutase activity EC 1. To confirm death, each animal was monitored for the following signs: In this first attempt at elucidating the molecular targets of anti-inflammatory actions of B. Results and Discussion 3. Blood samples were collected via ocular puncture with the aid of a capillary tube into EDTA ethylenediaminetetraacetic acid bottles and heparinized bottles for respective hematological and blood chemistry analysis.

Studies by electron paramagnetic resonance of the importance of iron in hydroxyl scavenging properties of ascorbic acid in plasma: The data were subjected to one-way analysis of variance ANOVA test and the differences between samples were determined by Dunnett’s multiple comparison tests, using the graph pad prism statistical software GraphPad Software Inc.

Traditional knowledge compared with a literature seach of modern pharmacology and toxicology. Antiulcer activity of an anthocyanidin from Vaccinium myrtillus. Should we be concerned about herbal remedies? Modulatory activity of antioxidants against the toxicity of rifampicin in vivo. Determination of brixelia acid Vitamin C Concentration was measured according to the method described by Benderitter et al. The acute lethal effect of the aqueous stem bark extract of Bridelia ferruginea on rats produced no death within 24 hours of treatment either via oral or intraperitoneal routes.

Effects of aqueous extract of garlic Allium sativum on testicular functions in the rat. Despite all these uses, extensive toxicological evaluation has not been carried out.


Studies on the efficacy of Bridelia ferruginea benth extract for water purification. Evidences supporting the importance of the p38 MAPK in inflammatory diseases, such as asthma, rheumatoid arthritis, systemic inflammation, inflammatory bowel disease, and brain inflammation, have been reviewed by Yong et al.

Taylor and Francis; Table 3 Effects of aqueous stem bark extract of Bridelia ferruginea on the body weights of rats. The reaction mixture 3 mL contained 0. Aqueous extract of Combretum dolichopentalum leaf-a potent inhibitor of carbon tetrachloride induced hepatotoxicity in rats. The p38 MAPK signalling has also been widely accepted as a cascade contributing to neuroinflammation [ 12 ].

West African Plants

Urea, the end product of protein metabolism, and its concentration is influenced by the rate of excretion, while creatinine is the waste product of muscle metabolism. Complement-inhibiting constituent of Bridelia ferruginea stem bark.

This may be due to the stimulatory effect of the extract on thrombopoietin. According to McKnight et al. Male Wistar albino mice average weight 20 g and male albino rats average weight g used in this study were obtained from ferrugineaa Laboratory Animal Center of the College of Medicine, University of Lagos, Lagos, Nigeria.

Morphological abnormalities were classified as headless sperm, banana head, bent neck and bent tail.